Grant
OREGON HEALTH & SCIENCE UNIVERSITY
$429,000
Department of Health and Human Services
Award ID
R35GM161749
Action Date
2026-04-01
Fiscal Year
FY 2026
Award Type
Grant
Place of Performance
PORTLAND, Oregon
Period of Performance
2026-04-01 → 2031-03-31
Funding Agency
Department of Health and Human Services
Description
STRUCTURE AND FUNCTION OF KATP CHANNELS - PROJECT SUMMARY ATP-SENSITIVE POTASSIUM (KATP) CHANNELS, GATED BY INTRACELLULAR NUCLEOTIDES ATP AND ADP, COUPLE CELL ENERGETICS WITH MEMBRANE EXCITABILITY TO GOVERN A WIDE RANGE OF PHYSIOLOGICAL PROCESSES VITAL TO ENERGY HOMEOSTASIS. KATP CHANNELS ARE UNIQUE HETERO-OCTAMERIC MEMBRANE PROTEIN COMPLEXES OF FOUR INWARD RECTIFIER K+ CHANNEL (KIR6.1 OR KIR6.2) SUBUNITS AND FOUR SULFONYLUREA RECEPTOR (SUR1, SUR2A, OR SUR2B) SUBUNITS. VARIOUS KIR6.X/SURX COMBIN
Recipient
Name
OREGON HEALTH & SCIENCE UNIVERSITY
State
OR
UEI
NPSNT86JKN51