Grant
TRUSTEES OF INDIANA UNIVERSITY
$415,822
Department of Health and Human Services
Award ID
R35GM161411
Action Date
2026-04-01
Fiscal Year
FY 2026
Award Type
Grant
Place of Performance
BLOOMINGTON, Indiana
Period of Performance
2026-04-01 → 2031-02-28
Funding Agency
Department of Health and Human Services
Description
OXIDATIVE PROTEIN FOLDING IN BACTERIA - OXIDATIVE PROTEIN FOLDING IN BACTERIA PROJECT SUMMARY OXIDATIVE PROTEIN FOLDING GENERATES COVALENT LINKAGES BETWEEN THE SULFUR ATOMS OF TWO CYSTEINE RESIDUES, KNOWN AS DISULFIDE BONDS (DSBS). DSBS PLAY A CRUCIAL ROLE IN THE THREE-DIMENSIONAL STRUCTURE AND BIOLOGICAL FUNCTION OF EXPORTED PROTEINS IN PROKARYOTES AND EUKARYOTES. SINCE THE DISCOVERY OF THE FIRST DSB CATALYST IN THE BACTERIUM ESCHERICHIA COLI, BACTERIA HAVE BEEN PROVEN TO BE A POWERFUL MODEL S
Recipient
Name
TRUSTEES OF INDIANA UNIVERSITY
State
IN
UEI
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