TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE

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THE ROLE OF PATERNAL T CELLS IN EPIGENETIC INHERITANCE OF SEBUM SECRETION - PROJECT SUMMARY: PARENTAL EXPERIENCES SUCH AS DIET AND STRESS CAN AFFECT THE PHENOTYPE OF SUBSEQUENT GENERATIONS THROUGH NON-GENETIC INHERITANCE. THIS PROCESS, WHERE PHENOTYPIC CHANGES ARE PASSED ON WITHOUT ALTERING THE DNA SEQUENCE, CAN ALTER PHENOTYPES OF THE F1 GENERATION OF MICE OR EVEN BEYOND. WHILE EPIGENETIC INHERITANCE TO THE F1 GENERATION IS WELL-ESTABLISHED IN MAMMALS, BEYOND THE F1 GENERATION TO THE F2 GENERAT

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